منابع مشابه
Regulation of hematopoiesis.
Normal hematopoiesis is a well-regulated process in which the generation of mature blood elements occurs from a primitive pluripotent stem cell in an ordered sequence of maturation and proliferation. Regulation occurs at the level of the structured microenvironment (stroma), via cell-cell interactions and by way of the generation of specific hormones and cytokines: erythropoietin, interleukin 3...
متن کاملT cell regulation of hematopoiesis.
It has long been known that thymus-derived lymphocytes (T cells) can produce cytokines that have powerful effects on hematopoiesis. All major classes of T cells--CD4 T helper cells, CD4 regulatory T cells, CD8 T cells, gammadelta T cells and NKT cells--produce a number of cytokines and chemokines that can modulate hematopoiesis. More recent research has shown that specific T helper cell types, ...
متن کاملCatecholaminergic regulation of hematopoiesis in mice.
The article by Benestad et al1 published in BLOOD states that murine bone marrow functions are not regulated by neuronal mechanisms. I am surprised by this drastic and final conclusion. Even the title, ‘‘No Neuronal Regulation of Murine Bone Marrow Function,’’ sounds more suitable for a popular press article. Actually, there are a number of observations that have been disregarded by the investi...
متن کاملRegulation of hematopoiesis through adhesion receptors.
Normal steady-state hematopoiesis takes place in the bone marrow microenvironment. Soluble factors as well as contact interactions between the hematopoietic cells and the marrow microenvironment dictate the fate of hematopoietic stem cells and progenitors. Over the last decade it has become clear that cell-cell and cell-extracellular matrix interactions through adhesion receptors play a major r...
متن کاملEpigenetic regulation of hematopoiesis by DNA methylation.
During embryonic development, cell type-specific transcription factors promote cell identities, while epigenetic modifications are thought to contribute to maintain these cell fates. Our understanding of how genetic and epigenetic modes of regulation work together to establish and maintain cellular identity is still limited, however. Here, we show that DNA methyltransferase 3bb.1 (dnmt3bb.1) is...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Pediatric Research
سال: 1990
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199005000-00001